Equipe Ostéoimmunologie, Niches et Inflammation

Responsable : Claudine Blin

[2017] Emerging roles of osteoclasts in the modulation of bone microenvironment and immune suppression in multiple myeloma. Frontiers in Immunology
Mansour A, Wakkach A, Blin-Wakkach C 08-08-2017
[2017] Osteoblastic heparan sulfate glycosaminoglycans control bone remodeling by regulating Wnt signaling and the crosstalk between bone surface and marrow cells. Cell Death Dis. 2017 Jun 29;8(6):e2902.
Mansouri R, Jouan Y, Hay E, Blin-Wakkach C, Frain M, Ostertag A, Le Henaff C, Marty C, Geoffroy V, Marie PJ, Cohen-Solal M, Modrowski D. 08-08-2017
[2016] Inflammatory osteoclasts prime TNFα-producing CD4+ T cells and express CX3CR1. Journal of Bone and Mineral Research 2016, Oct;31(10):1899-1908.
L. Ibáñez, G. Abou-Ezzi, T. Ciucci, V. Amiot, N. Belaïd, D. Obino, A. Mansour, M. Rouleau, A. Wakkach, C. Blin-Wakkach. 07-05-2016
[2016] Dendritic Cell-Derived Osteoclast: a new game changer in bone resorption-associated diseases. Drug Discovery Today. In press
Laperine O, Blin-Wakkach C, Guicheux J, Beck-Cormier S, Lesclous P. 07-05-2016
[2016] BCL-B (BCL2L10) is overexpressed in patients suffering from multiple myeloma (MM) and drives a MM-like disease in transgenic mice. J Exp Med. 2016, In press
Hamoude MA , Jacquel A, Robert G, Puissant A, Richez V, Cassel R , Fenouille N, Roulland S, Gilleron J, Griessinger E, Dubois A, Bailly-Maitre B, Goncalvès D, Mallavialle A, Colosetti P, Marchetti S, Amiot A, Gomez-Bougie P, Rochet N, Deckert M, Avet-Loiseau H, Hofman P, Karsenti JM, Jeandel PY, Blin-Wakkach C, Nadel B, Cluzeau T, Anderson KC, Fuzibet JG, Auberger P, Luciano F 06-06-2016
[2016] Modeling Andersen's Syndrome in Human Induced Pluripotent Stem Cells. Stem Cells Dev. 2016 Jan 15;25(2):151-9.
Pini J, Rouleau M, Desnuelle C, Sacconi S, Bendahhou 19-01-2016
[2015] Osteoimmune Interactions in Inflammatory Bowel Disease: Central Role of Bone Marrow Th17 TNFα Cells in Osteoclastogenesis. Frontiers in Immunology. 18 Dec 2015
Wakkach A, Rouleau M, and Blin-Wakkach C 23-12-2015
[2015] Glycolysis-Mediated Changes in Acetyl-CoA and Histone Acetylation Control the Early Differentiation of Embryonic Stem Cells. Cell Metab. Mar 3;21(3):392-402
Moussaieff A, Rouleau M, Kitsberg D, Cohen M, Levy G, Barasch D, Nemirovski A, Shen-Orr S, Laevsky I, Amit M, Bomze D, Elena-Herrmann B, Scherf T, Nissim-Rafinia M, Kempa S, Itskovitz-Eldor J, Meshorer E, Aberdam D, Nahmias Y. 27-07-2015
[2015] Local mitochondrial-endolysosomal microfusion cleaves the voltage-dependent anion channel 1 to promote survival in hypoxia. Mol Cell Biol. Feb 17. pii: MCB.01402-14.
Brahimi-Horn MC, Lacas-Gervais S, Adaixo R, Ilc K, Rouleau M, Notte A, Dieu M, Michels C, Voeltzel T, Maguer-Satta V, Pelletier J, Ilie M, Hofman P, Manoury B, Schmidt A, Hiller S, Pouysségur J, Mazure NM. 27-07-2015
[2015] Bone marrow Th17 TNFα cells induce osteoclast differentiation, and link bone destruction to IBD. Gut. Jul;64(7):1072-81.
Ciucci T, Ibáñez L, Boucoiran A, Birgy-Barelli E, Pène J, Abou-Ezzi G, Arab N, Rouleau M, Hébuterne X, Yssel H, Blin-Wakkach C, Wakkach A 27-07-2015
[2014] Roles of osteoclasts in the control of medullary hematopoietic niches. Arch Biochem Biophys. Nov 1;561C:29-37.
Blin-Wakkach C, Rouleau M, Wakkach A. 27-07-2015
[2014] Angiomodulin is required for cardiogenesis of embryonic stem cells and is maintained by a feedback loop network of p63 and Activin-A. Stem Cell Res. Jan;12(1):49-59.
Wolchinsky Z, Shivtiel S, Kouwenhoven EN, Putin D, Sprecher E, Zhou H, Rouleau M, Aberdam D. 27-07-2015
[2012] Osteoclasts promote the formation of hematopoietic stem cell niches in the bone marrow. J Exp Med. Mar 12;209(3):537-49
Mansour A, Abou-Ezzi G, Sitnicka E, Jacobsen SE, Wakkach A, Blin-Wakkach C 27-07-2015
[2012] Identification of adipose tissue dendritic cells correlated with obesity-associated insulin-resistance and inducing Th17 responses in mice and patients. Diabetes. Sep;61(9):2238-47.
Bertola A*, Ciucci T*, Rousseau D, Bourlier V, Duffaut C, Bonnafous S, Blin-Wakkach C, Anty R, Iannelli A, Gugenheim J, Tran A, Bouloumié A, Gual P, Wakkach A. *Equal contribution 27-07-2015
[2012] Role of osteoclasts in the hematopoietic stem cell niche formation. Cell Cycle. Jun 1;11(11):2045-6.
Mansour A, Wakkach A, Blin-Wakkach C. 27-07-2015
[2012] Regulation of skin aging and heart development by TAp63. Cell Death Differ 2012; 19(2): 186-93.
Paris M, Rouleau M, Puceat M, Aberdam D. 27-07-2015
[2012] Severe Thymic Atrophy in a Mouse Model of Skin Inflammation Accounts for Impaired TNFR1 Signaling. PLoS One. 7(10):e47321
Belhacéne N, Gamas P, Gonçalvès D, Jacquin M, Beneteau M, Jacquel A, Colosetti P, Ricci JE, Wakkach A, Auberger P, Marchetti S. 27-07-2015
[2012] Expression of a truncated active form of VDAC1 in lung cancer associates with hypoxic cell survival and correlates with progression to chemotherapy resistance. Cancer Res. 72(8): 2140-2150.
Brahimi-Horn MC, Ben-Hail D, Ilie M, Gounon P, Rouleau M, Hofman V, Doyen J, Mari B, Shoshan-Barmatz V, Hofman P, Pouysségur J and Mazure NM. 27-07-2015
[2011] Osteoclast activity modulates B-cell development in the bone marrow. Cell Res. Jul;21(7):1102-15.
Mansour A, Anginot A, Mancini SJ, Schiff C, Carle GF, Wakkach A, Blin-Wakkach C. 27-07-2015
[2011] TAp63 is important for cardiac differentiation of embryonic stem cells and heart development. Stem Cells; 29(11): 1672-83
Rouleau M, Medawar A, Hamon L, Shivtiel S, Wolchinsky Z, Zhou H, De Rosa L, Candi E, de la Forest Divonne S, Mikkola ML, van Bokhoven H, Missero C, Melino G, Puceat M and Aberdam D. 27-07-2015
[2011] Unexpected role for p63 during heart development: one phenotype can hyde another one. Med Sci (Paris); 27(10): 905-9.
Rouleau M, Puceat M, Aberdam D. 27-07-2015
[2011] MicroRNA-34a regulates neurite outgrowth, spinal morphology, and function. Proc Natl Acad Sci U S A.; 108(52):21099-104.
Agostini M, Tucci P, Steinert JR, Shalom-Feuerstein R, Rouleau M, Aberdam D, Forsythe ID. Young KW, Ventura A, Concepcion CP, Han YC, Candi E, Knight RA, Mak TW, Melino, G. 27-07-2015
[2010] Inflammatory blood monocytes contribute to tumor development and represent a privileged target to improve host immunosurveillance. J Immunol. 2010 Dec 15;185(12):7165-73
Augier S, Ciucci T, Luci C, Carle GF, Blin-Wakkach C, Wakkach A. 27-07-2015
[2010] Bone resorption control of tooth eruption and root morphogenesis: involvement of the receptor activator of NF-kappaB (RANK). J Cell Physiol. Jul 15. [Epub ahead of print].
Castaneda B, Simon Y, Jacques J, Hess E, Choi YW, Blin-Wakkach C, Mueller C, Berdal A, Lézot F. 27-07-2015
[2009] More on the differentiation of dendritic cells into osteoclasts, Blood. Jan, 113(1): 265
Wakkach A, Blin-Wakkach C. 27-07-2015
[2008] Bone marrow microenvironment controls the in vivo differentiation of murine dendritic cells into osteoclasts. Blood. Dec 15;112(13):5074-83
Wakkach A, Mansour A, Dacquin R, Coste E, Jurdic P, Carle GF, Blin-Wakkach C. 27-07-2015
[2008] Characterization of IL-10-secreting T cells derived from regulatory CD4+CD25+ cells by the TIRC7 surface marker. J Immunol. May 1;180(9):6054-63
Wakkach A, Augier S, Breittmayer JP, Blin-Wakkach C, Carle GF. 27-07-2015
[2010] 3BP2 Adapter protein is required for receptor activator of NfkappaB ligand (RANKL)-induced osteoclast differentiation of RAW264.7 cells. J Biol Chem. Jul 2;285(27):20952-63
GuezGuez A, Prod'homme V, Mouska X, Baudot A, Blin-Wakkach C, Rottapel R, Deckert M. 27-07-2015
[2010] Dlx homeobox gene family expression in osteoclasts. J Cell Physiol. Jun;223(3):779-87.
Lézot F, Thomas BL, Blin-Wakkach C, Castaneda B, Bolanos A, Hotton D, Sharpe PT, Heymann D, Carles GF, Grigoriadis AE, Berdal A. 27-07-2015
[2010] Hypoxic enlarged mitochondria protect cancer cells from apoptotic stimuli. J. Cell. Physiol. 222:648-57
Chiche J, Rouleau M, Gounon P, Brahimi-Horn MC, Pouysségur J, Mazure NM. 27-07-2015
[2009] Elevated expression of osteopontin may be related to adipose tissue macrophage accumulation and liver steatosis in morbid obesity. Diabetes. Jan;58(1):125-33.
Bertola A, Deveaux V, Bonnafous S, Rousseau D, Anty R, Wakkach A, Dahman M, Tordjman J, Clément K, McQuaid SE, Frayn KN, Huet PM, Gugenheim J, Lotersztajn S, Le Marchand-Brustel Y, Tran A, Gual P. 27-07-2015
[2009] Dax-1 Knockdown In Mouse Embryonic Stem Cells Induces Loss of Pluripotency and Multilineage Differentiation. Stem Cells. 2009, 27:1529-37.
Khalfallah O, Rouleau M, Barbry P, Bardoni B, Lalli E. 27-07-2015
[2008] A pure population of ectodermal cells derived from human embryonic stem cells. Stem Cells. 26:440-4
Aberdam E, Barak E, Rouleau M, de LaForest S, Berrih-Aknin S, Suter DM, Krause KH, Amit M, Itskovitz-Eldor J, Aberdam D. 27-07-2015
[2008] DeltaNp63 is essential for epidermal commitment of embryonic stem cells. PLoS One. 3:e3441.
Medawar A, Virolle T, Rostagno P, de la Forest-Divonne S, Gambaro K, Rouleau M *, Aberdam D*.* equal contribution. 27-07-2015